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Lifestyle

Stopping & the yo-yo effect

After stopping GLP-1 medication, the weight often partly comes back, because the appetite-suppressing effect disappears. A lasting lifestyle change and good guidance are therefore important to maintain results. When and how you stop or taper off should always be discussed with your doctor.

Why does weight come back?

GLP-1 medicines suppress appetite and give a feeling of fullness. If you stop, this effect disappears and appetite often returns to its old level. Without a change in lifestyle, part of the lost weight may therefore return, the so-called yo-yo effect.

Lifestyle as a foundation

The medicine is an aid, not a substitute for healthy habits. By already working on nutrition, physical activity and behaviour during the course, you increase the chance that the result is sustainable.

  • A healthy and varied eating pattern with enough protein;
  • Regular physical activity to preserve muscle mass and fitness;
  • Attention to sleep, stress and eating behaviour.

Maintenance and tapering off

Some people use GLP-1 medication long-term as maintenance, others taper off at some point. What is appropriate differs from person to person and depends on your health and goals. Never just stop on your own initiative; tapering off in consultation with your doctor allows for a smooth transition.

Are you considering stopping or tapering off? Discuss this with your treating doctor first.

Frequently asked questions

Will my weight come back if I stop?
Often part of the weight comes back, because the appetite-suppressing effect disappears. A lasting lifestyle change increases the chance that you maintain your result.
How do I prevent the yo-yo effect?
By continuing to work on healthy nutrition, physical activity and behaviour during and after the course. Guidance from a doctor or dietitian can help with this.
How long should I use GLP-1?
That differs from person to person and should be discussed with your doctor. Some people use it long-term, others taper off at some point. Read more under how long to use it.
Can I stop my GLP-1 medicine on my own?
Do not just stop on your own initiative. Discuss stopping or tapering off with your treating doctor, so that this is done in a responsible way.

Official sources on this topic

Independent, authoritative information from official bodies: