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Weight-loss injection & slimming injection

'Weight-loss injection', 'slimming injection' and 'slimming pen' are everyday terms for the same group of medicines: the GLP-1 injections such as Ozempic, Wegovy, Mounjaro and Saxenda. These are all prescription-only medicines that a doctor assesses and that are supplied through a pharmacy. On this page we explain factually what the weight-loss injection is, which ones exist, what it costs and what to look out for.

What is a weight-loss injection?

The 'weight-loss injection' is not a separate medicine, but the popular name for GLP-1 injections that suppress appetite. They mimic the body's own hormone GLP-1, making you feel full sooner and for longer so you eat less. You can read exactly how this works on how GLP-1 medicines work. The terms 'slimming injection', 'slimming pen', 'weight-loss pen' and 'slimming shot' all refer to the same thing. A doctor decides whether such a medicine is right for you.

Which weight-loss injections are there?

The best-known weight-loss injections in the Netherlands:

MedicineActive ingredientFrequency
OzempicSemaglutideWeekly injection
WegovySemaglutideWeekly injection
MounjaroTirzepatideWeekly injection
SaxendaLiraglutideDaily injection

Prefer not to inject? There are also tablets such as Rybelsus and Mysimba — see pill or injection. If you're unsure which medicine to choose, read Ozempic or Mounjaro.

How does the slimming pen work?

A slimming pen is a pre-filled injection pen with which you administer the medicine under the skin (abdomen, thigh or upper arm). The dose is built up gradually to limit side effects — see dosing & titration and how injecting works. Always follow the package leaflet and the instructions from your doctor and pharmacy.

What does a weight-loss injection cost?

There is no fixed price: it depends on the medicine, the dose and the provider. As a rough guide, monthly costs range from around €150 to €500+. Work it out with our cost calculator and compare providers on the clinics page. For weight loss, the weight-loss injection is usually not covered by insurance; read more on insurance coverage.

Side effects, safety & prescription

The most common side effects are gastrointestinal complaints (nausea, diarrhoea); see side effects of Ozempic and of Mounjaro. A weight-loss injection is prescription-only: you cannot legally buy it without a prescription, and counterfeits sold through dubious web shops are a real danger — read how to spot counterfeits and are weight-loss medicines dangerous?.

Prescription-only and not medical advice: a doctor always assesses whether a weight-loss injection is safe and suitable for you.

Who is it for & how do you start?

A weight-loss injection is generally intended for obesity (BMI of 30 or above) or for being overweight (BMI of 27 or above) with a weight-related condition — see who is it suitable for. You start with an intake in which a doctor assesses your eligibility (the doctor's intake). Compare the providers and their support on the clinics page.

Frequently asked questions

What is the weight-loss injection?
'Weight-loss injection' is the everyday term for GLP-1 injections such as Ozempic, Wegovy, Mounjaro and Saxenda. They suppress appetite and are prescription-only; a doctor assesses whether they are suitable.
Which weight-loss injection is best?
It varies from person to person. Mounjaro (tirzepatide) produces the most weight loss on average in studies, but 'best' depends on your situation, tolerability and budget. A doctor advises you.
Can you buy a weight-loss injection without a prescription?
No. Weight-loss injections are prescription-only in the Netherlands and available only through a doctor and pharmacy. Anything offered without a prescription is illegal and risky (counterfeits).
What does a weight-loss injection cost per month?
As a rough guide, around €150 to €500+, depending on the medicine, dose and provider. Work it out with the cost calculator and compare clinics.