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Ozempic or Mounjaro?

The main difference: Mounjaro (tirzepatide) works on two receptors (GLP-1 and GIP) and produces more weight loss on average, while Ozempic (semaglutide) works on a single receptor and is usually cheaper. Which one is suitable is always assessed by a doctor.

The main difference

  • Ozempic: semaglutide, GLP-1, usually cheaper
  • Mounjaro: tirzepatide, GLP-1 and GIP, stronger effect on average, usually more expensive
  • Both: weekly injection, prescription-only, similar types of side effects

Weight loss and side effects

In clinical studies, tirzepatide produces more weight loss on average than semaglutide. The nature of the side effects (mainly gastrointestinal) is similar. Individual results vary.

Cost comparison

Ozempic/semaglutide is cheaper than Mounjaro/tirzepatide at most providers. Compare the current price per medicine and per clinic in our comparison tool and cost calculator.

Frequently asked questions

Which works better, Ozempic or Mounjaro?
Mounjaro produces more weight loss on average in studies, but 'better' depends on your medical situation, tolerability and budget. A doctor advises you.
Is Mounjaro more expensive than Ozempic?
Yes, Mounjaro (tirzepatide) is usually more expensive than Ozempic (semaglutide).