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Lifestyle

Alcohol & GLP-1

There is no general legal ban on alcohol while using GLP-1 medication such as semaglutide or tirzepatide, but moderation is wise. Alcohol can worsen stomach complaints, affect your blood sugar and provides extra calories. What applies to your situation and medicine is stated in the package leaflet and should be discussed with your doctor or pharmacist.

Alcohol and gastrointestinal complaints

GLP-1 medicines slow down gastric emptying, which can cause nausea, a feeling of fullness and other gastrointestinal complaints, especially at the start of a course or after a dose increase. Alcohol can further irritate the stomach and worsen these complaints.

Many users notice that they tolerate alcohol less well or have less need for it. Listen to your body and discuss persistent complaints with your healthcare provider.

Effect on blood sugar

Alcohol can affect blood sugar levels. On their own, GLP-1 medicines rarely cause low blood sugar (hypoglycaemia), but the risk may increase in combination with certain diabetes medication, such as insulin or sulfonylureas.

Are you using other diabetes medicines alongside GLP-1? Then discuss with your doctor how alcohol may affect your blood sugar.

Calories and your weight-loss goal

Alcohol provides relatively many calories without nutritional value. During a course aimed at weight loss, drinking regularly can work against your goal. In addition, alcohol can influence appetite and inhibitions, making it easier to eat more.

  • A glass of wine or beer already contains a considerable amount of calories.
  • Mixed drinks and liqueurs often contain extra sugars.
  • Drinking enough water remains important, certainly with gastrointestinal complaints.

What is sensible?

A general recommendation is to use alcohol in moderation and pay close attention to your own reaction. Whether specific restrictions apply to you depends on your medicine, your health and any other medication. Consult the package leaflet of your medicine and the Farmacotherapeutisch Kompas, and discuss any doubts with your doctor or pharmacist.

Frequently asked questions

Can I drink alcohol during a GLP-1 course?
There is no general ban, but moderation is recommended. Alcohol can worsen stomach complaints, affect blood sugar and provides extra calories. Read the package leaflet and consult your doctor.
Does alcohol worsen the side effects of GLP-1?
Alcohol can irritate the stomach and thus worsen nausea and a feeling of fullness, especially at the start of the course. Many users tolerate alcohol less well than before.
Can alcohol cause low blood sugar?
GLP-1 medicines themselves rarely cause low blood sugar, but in combination with insulin or certain other diabetes medicines the risk may increase. Discuss this with your doctor.

Official sources on this topic

Independent, authoritative information from official bodies: